The Panthers return home to the UNI-Dome where they are 3-0 on the year. UNI is 3-3 after a tough loss to No. 1 North Dakota State in Fargo. According to Massey Ratings, UNI has faced the toughest schedule to date in the FCS. The Panthers host a South Dakota team who is 3-3 on the year, but 3-0 in the last three games. The game is the 50th in the series and UNI leads 29-19-1, including an 8-2 record since South Dakota joined the ranks of Division I.

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