That hasn't stopped SLU, being on an island.
You've also got Dayton.
But I doubt SLU ends up in the Big East
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The only reason for St. Louis to stay in the A-10 is because it's the best jumping off point to get into the Big East.
St. Louis would be the next school to get into the Big East (other than Notre Dame if they ever decide to not continue their current deal with the ACC for whatever reason) because of it's presence in a "major league" media market that also doesn't have an NBA team.